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WHAT IS DUKORAL®?
DUKORAL® is a vaccine that helps protect against cholera – it is provided as a convenient drinkable formulation.1
DUKORAL® is an inactivated vaccine, so there’s no risk of transmission from vaccine recipients to non-vaccinated close contacts (e.g., family members).1,2
DUKORAL® was the first cholera vaccine licensed for use in the UK.3
DUKORAL® INDICATION
DUKORAL® is licensed for adults, adolescents, and children aged two years or older who are travelling to at-risk areas for cholera.1
DUKORAL® CONTRAINDICATIONS
The vaccine is contraindicated in individuals who have had an anaphylactic reaction to any vaccine component or formaldehyde. For a full list of vaccine components, please see the summary of product characteristics.1
Administration of DUKORAL® should be postponed for patients suffering from acute gastrointestinal illness or acute febrile illness.1
DUKORAL® KEY FACTS
ADMINISTER WITH EASE
Can be reconstituted in any still, drinkable water – even from the tap.1
WIDE AGE RANGE
Can be given to people aged ≥2 years old travelling to at-risk areas.1
EFFECTIVE PROTECTION
85% efficacy at six months, proven in large field studies and mass vaccination campaigns.1
SUITABLE FOR LAST-MINUTE TRAVEL
Can be started as late as 14 days before departure (≥6 years old).1
GENERALLY WELL TOLERATED
Confirmed by decades of post-marketing experience, with millions of doses distributed.1,4,5
PRODUCT CHARACTERISTICS
Each dose of DUKORAL® contains inactivated Vibrio cholera O1 bacteria and the recombinant non-toxic B-subunit of the cholera toxin (rCTB).1
Immunisation protects specifically against V. cholerae serogroup O1 and is not a substitute for adhering to protective hygiene measures.1
VACCINE STORAGE AND HANDLING
DUKORAL® should be stored in a refrigerator at 2–8°C1
Do not freeze1
DUKORAL® has a shelf life of three years1
Product in the unopened vial and sachet, stored in the outer carton, is stable at temperatures up to 25oC for a period of 14 days1
At the end of this period the product should be used or discarded1
LEARN MORE ABOUT DUKORAL®
Delve deeper into the product features, clinical findings, and dosing recommendations.
DUKORAL® suspension and effervescent powder for oral suspension
CLINICAL DATA
Explore the latest clinical data on the efficacy and safety profile of DUKORAL®.
DUKORAL® suspension and effervescent powder for oral suspension
DOSING & ADMINISTRATION
DUKORAL® is administered orally in two doses for adults, and three for children <6 years.
References
- DUKORAL®. Summary of Product Characteristics. February 2023. Available at: https://www.medicines.org.uk/emc/product/5087/smpc. Accessed: August 2026.
- Sanders B, Koldijk M, Schuitemaker H. Inactivated Viral Vaccines. Vaccine Analysis: Strategies, Principles, and Control.:45-80.
- NaTHNaC Travel Health Pro. Cholera. August 2024. Available at: https://travelhealthpro.org.uk/factsheet/56/cholera. Accessed: August 2026.
- VALNEVA Announces Successful Establishment of New Global Marketing and Distribution Network | Fierce Pharma. January 2016. Available at: https://www.fiercepharma.com/vaccines/valneva-announces-successful-establishment-of-new-global-marketing-and-distribution. Accessed: August 2026.
- World Health Organization. Immunization, Vaccines and Biologicals. Available at: https://www.who.int/teams/immunization-vaccines-and-biologicals/diseases/cholera. Accessed: August 2026.
UK-DUK-2600001 (v2.0) August 2026